CK2-Mediated Phosphorylation Upregulates the Stability of USP13 and Promotes Ovarian Cancer Cell Proliferation

CK2-Mediated Phosphorylation Upregulates the Stability of USP13 and Promotes Ovarian Cancer Cell Proliferation

Ubiquitin-specific Peptidase 13 (USP13) is a deubiquitinating enzyme that regulates the stability or function of its substrate. USP13 is highly amplified in human ovarian cancer, and elevated expression of USP13 promotes tumorigenesis and metastasis of ovarian cancer. However, there is little known...

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Bibliographic Details
Main Authors: Juntae Kwon, Jinmin Zhang, Boram Mok, Cecil Han
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
ovarian cancer
USP13
post-translational modification
phosphorylation
Online Access:https://www.mdpi.com/2072-6694/15/1/200

Internet

https://www.mdpi.com/2072-6694/15/1/200

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