Investigating the mechanism by which SMAD3 induces PAX6 transcription to promote the development of non-small cell lung cancer

Investigating the mechanism by which SMAD3 induces PAX6 transcription to promote the development of non-small cell lung cancer

Abstract Background This study investigated the function of SMAD3 (SMAD family member 3) in regulating PAX6 (paired box 6) in non-small cell lung cancer. Methods First, qRT-PCR was employed to detect SMAD3 expression in cancer tissues along with normal tissues and four cell lines, including BEAS-2B,...

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Bibliographic Details
Main Authors: Zhe Qian, Qiankun Zhang, Ying Hu, Tongmei Zhang, Jie Li, Zan Liu, Hua Zheng, Yuan Gao, Wenyun Jia, Aimin Hu, Baolan Li, Jiqing Hao
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Respiratory Research
Subjects:
Non-small cell lung cancer
SMAD3
PAX6
Online Access:http://link.springer.com/article/10.1186/s12931-018-0948-z

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http://link.springer.com/article/10.1186/s12931-018-0948-z

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