Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Ductal Adenocarcinoma (PDAC)

Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients with Pancreatic Ductal Adenocarcinoma (PDAC)

Deficient DNA mismatch repair status (dMMR)/high microsatellite instability have been shown to be predictive biomarkers for immune checkpoint inhibitor drugs which block the programmed death protein-1/programmed death ligand-1 (PD-1/PD-L1) interaction between tumor cells and activated T cells. The a...

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Bibliographic Details
Main Authors: Alina Constantin, Vlad Iovănescu, Irina Mihaela Cazacu, Bogdan Silviu Ungureanu, Cătălin Copăescu, Cezar Stroescu, Nona Bejinariu, Adrian Săftoiu
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Diagnostics
Subjects:
pancreatic ductal adenocarcinoma
endoscopic ultrasound-guided fine-needle biopsy
PD-L1
MMR expression
Online Access:https://www.mdpi.com/2075-4418/12/2/294

Internet

https://www.mdpi.com/2075-4418/12/2/294

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