aRNAque: an evolutionary algorithm for inverse pseudoknotted RNA folding inspired by Lévy flights

aRNAque: an evolutionary algorithm for inverse pseudoknotted RNA folding inspired by Lévy flights

Abstract Background We study in this work the inverse folding problem for RNA, which is the discovery of sequences that fold into given target secondary structures. Results We implement a Lévy mutation scheme in an updated version of aRNAque an evolutionary inverse folding algorithm and apply it to...

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Bibliographic Details
Main Authors: Nono S. C. Merleau, Matteo Smerlak
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Bioinformatics
Subjects:
RNA inverse folding
Pseudoknotted RNAs
Evolutionary algorithm (EA)
Lévy flight
Online Access:https://doi.org/10.1186/s12859-022-04866-w

Internet

https://doi.org/10.1186/s12859-022-04866-w

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