Comparison of T790M Acquisition After Treatment With First- and Second-Generation Tyrosine-Kinase Inhibitors: A Systematic Review and Network Meta-Analysis

Comparison of T790M Acquisition After Treatment With First- and Second-Generation Tyrosine-Kinase Inhibitors: A Systematic Review and Network Meta-Analysis

BackgroundLung adenocarcinoma is a common disease with a high mortality rate. Epidermal growth factor receptor (EGFR) mutations are found in adenocarcinomas, and oral EGFR-tyrosine kinase inhibitors (EGFR-TKIs) show good responses. EGFR-TKI therapy eventually results in resistance, with the most com...

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Bibliographic Details
Main Authors: Po-Chun Hsieh, Yao-Kuang Wu, Chun-Yao Huang, Mei-Chen Yang, Chan-Yen Kuo, I-Shiang Tzeng, Chou-Chin Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
adenocarcinoma
epidermal growth factor receptor
tyrosine kinase inhibitors
T790M acquisition
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.869390/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.869390/full

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