Engineering species-like barriers to sexual reproduction

Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.

Bibliographic Details
Main Authors: Maciej Maselko, Stephen C. Heinsch, Jeremy M. Chacón, William R. Harcombe, Michael J. Smanski
Format: Article
Language:English
Published: Nature Portfolio 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01007-3