Engineering species-like barriers to sexual reproduction
Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-01007-3 |
| _version_ | 1818751836528574464 |
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| author | Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski |
| author_facet | Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski |
| author_sort | Maciej Maselko |
| collection | DOAJ |
| description | Genetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations. |
| first_indexed | 2024-12-18T04:41:54Z |
| format | Article |
| id | doaj.art-acabf95d0c834ff197052d558dcbfeae |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-18T04:41:54Z |
| publishDate | 2017-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-acabf95d0c834ff197052d558dcbfeae2022-12-21T21:20:41ZengNature PortfolioNature Communications2041-17232017-10-01811710.1038/s41467-017-01007-3Engineering species-like barriers to sexual reproductionMaciej Maselko0Stephen C. Heinsch1Jeremy M. Chacón2William R. Harcombe3Michael J. Smanski4Department of Biochemistry, Molecular Biology, and Biophysics and BioTechnology Institute, University of Minnesota – Twin CitiesDepartment of Biochemistry, Molecular Biology, and Biophysics and BioTechnology Institute, University of Minnesota – Twin CitiesDepartment of Ecology, Evolution, and Behavior and BioTechnology Institute, University of Minnesota – Twin CitiesDepartment of Ecology, Evolution, and Behavior and BioTechnology Institute, University of Minnesota – Twin CitiesDepartment of Biochemistry, Molecular Biology, and Biophysics and BioTechnology Institute, University of Minnesota – Twin CitiesGenetic isolation of a genetically modified organism represents a useful strategy for biocontainment. Here the authors use dCas9-VP64-driven gene expression to construct a ‘species-like’ barrier to reproduction between two otherwise compatible populations.https://doi.org/10.1038/s41467-017-01007-3 |
| spellingShingle | Maciej Maselko Stephen C. Heinsch Jeremy M. Chacón William R. Harcombe Michael J. Smanski Engineering species-like barriers to sexual reproduction Nature Communications |
| title | Engineering species-like barriers to sexual reproduction |
| title_full | Engineering species-like barriers to sexual reproduction |
| title_fullStr | Engineering species-like barriers to sexual reproduction |
| title_full_unstemmed | Engineering species-like barriers to sexual reproduction |
| title_short | Engineering species-like barriers to sexual reproduction |
| title_sort | engineering species like barriers to sexual reproduction |
| url | https://doi.org/10.1038/s41467-017-01007-3 |
| work_keys_str_mv | AT maciejmaselko engineeringspecieslikebarrierstosexualreproduction AT stephencheinsch engineeringspecieslikebarrierstosexualreproduction AT jeremymchacon engineeringspecieslikebarrierstosexualreproduction AT williamrharcombe engineeringspecieslikebarrierstosexualreproduction AT michaeljsmanski engineeringspecieslikebarrierstosexualreproduction |