Activation of PI3K/Akt pathway by G protein‐coupled receptor 37 promotes resistance to cisplatin‐induced apoptosis in non‐small cell lung cancer

Activation of PI3K/Akt pathway by G protein‐coupled receptor 37 promotes resistance to cisplatin‐induced apoptosis in non‐small cell lung cancer

Abstract Objectives Lung cancer is a major public health concern and represents the most common cause of cancer‐related death worldwide. Among eukaryotes, the G protein‐coupled receptor (GPCR) family stands as the largest group of membrane proteins. Alterations in GPCR gene expression and dysregulat...

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Bibliographic Details
Main Authors: Han Liu, Yingjie Zhu, Huikun Niu, Jing Jie, Shucheng Hua, Xiaoxue Bai, Shuai Wang, Lei Song
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Cancer Medicine
Subjects:
cisplatin
EMT
GPR37
NSCLC
PI3K/Akt pathway
Online Access:https://doi.org/10.1002/cam4.6543

Internet

https://doi.org/10.1002/cam4.6543

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