The gut microbiota reduces colonization of the mesenteric lymph nodes and IL-12-independent IFN-γ production during Salmonella infection

The intestinal commensal microbiota is essential for many host physiological processes, but its impact on infectious diseases is poorly understood. Here we investigate the influence of the gut microbiota during oral Salmonella infection. We report a higher bacterial burden in mesenteric lymph nodes...

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Bibliographic Details
Main Authors: Maria eFernandez-Santoscoy, Ulf Alexander Wenzel, Ulf eYrlid, Susanna eCardell, Fredrik eBäckhed, Mary Jo eWick
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2015.00093/full