The heat shock protein Hsc70-3 mediates an anti-apoptotic response critical for Plasmodium evasion of Anopheles gambiae immunity

The heat shock protein Hsc70-3 mediates an anti-apoptotic response critical for Plasmodium evasion of Anopheles gambiae immunity

ABSTRACT The mosquito immune system limits Plasmodium infection and malaria transmission. Plasmodium falciparum evades the mosquito defense response by expressing the surface protein P. falciparum P47 (Pfs47) that inhibits midgut epithelial nitration by interacting with the mosquito midgut P47 recep...

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Bibliographic Details
Main Authors: Thiago Luiz Alves e Silva, Gaspar E. Canepa, Brendan Sweeney, Patricia Hessab Alvarenga, Ming Zhao, Joel Vega-Rodríguez, Alvaro Molina-Cruz, Carolina Barillas-Mury
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
malaria
Plasmodium falciparum
Anopheles gambiae
mosquito
immune evasion
Pfs47
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00940-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00940-23

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