DNMTs inhibitor Procyanidin B2 reactivates PTEN’s regulatory effects on abnormal glucose metabolism in gastric cancer
Tumor suppressor PTEN was aberrant silenced in gastric cancer (GC) in our previous study. Activation of PTEN through DNA demethylation is a potential strategy for the treatment of GC. Procyanidin B2 (PB2), an effective DNMT inhibitor, exert positive effects on various diseases. In our work, PB2 supp...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Elsevier
2024-03-01
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| 叢編: | Journal of Functional Foods |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S1756464624000550 |