Effects of the Lipophilic Core of Polymer Nanoassemblies on Intracellular Delivery and Transfection of siRNA
Despite effective gene silencing in vitro, in vivo delivery and transfection of siRNA remain challenging due to the lack of carriers that protect siRNA stably in the body. This study is focused to elucidate the correlation between complex stability and transfection efficiency of siRNA carriers. The...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-07-01
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Series: | AIMS Biophysics |
Subjects: | |
Online Access: | http://www.aimspress.com/biophysics/article/345/fulltext.html |