Nanopore sequencing for detecting reciprocal translocation carrier status in preimplantation genetic testing

Nanopore sequencing for detecting reciprocal translocation carrier status in preimplantation genetic testing

Abstract Background Balanced reciprocal translocation (BRT) is one of the most common chromosomal abnormalities that causes infertility, recurrent miscarriage, and birth defects. Preimplantation genetic testing (PGT) is widely used to select euploid embryos for BRT carriers to increase the chance of...

Full description

Bibliographic Details
Main Authors: Qiuping Xia, Shenglan Li, Taoli Ding, Zhen Liu, Jiaqi Liu, Yanping Li, Huimin Zhu, Zhongyuan Yao
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Genomics
Subjects:
Nanopore sequencing
Reciprocal translocation
Breakpoints
MaReCs
PGT-SR
Preimplantation genetic testing
Online Access:https://doi.org/10.1186/s12864-022-09103-5

Internet

https://doi.org/10.1186/s12864-022-09103-5

Similar Items