The Impact of <i>MGMT</i> Promoter Methylation and Temozolomide Treatment in Serbian Patients with Primary Glioblastoma

The Impact of <i>MGMT</i> Promoter Methylation and Temozolomide Treatment in Serbian Patients with Primary Glioblastoma

<i>Background and objective:</i> Despite recent advances in treatment, glioblastoma (GBM) remains the most lethal and aggressive brain tumor. A continuous search for a reliable molecular marker establishes the methylation status of the O6-methylguanine-DNA methyltransferase (<i>MGM...

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Bibliographic Details
Main Authors: Nikola Jovanović, Tatjana Mitrović, Vladimir J. Cvetković, Svetlana Tošić, Jelena Vitorović, Slaviša Stamenković, Vesna Nikolov, Aleksandar Kostić, Nataša Vidović, Miljan Krstić, Tatjana Jevtović-Stoimenov, Dušica Pavlović
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Medicina
Subjects:
glioblastoma
<i>MGMT</i> methylation
temozolomide
overall survival
prognosis
methylation-specific polymerase chain reaction (MSP)
Online Access:https://www.mdpi.com/1010-660X/55/2/34

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https://www.mdpi.com/1010-660X/55/2/34

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