Translational reprogramming as a driver of antimony-drug resistance in Leishmania

Abstract Leishmania is a unicellular protozoan that has a limited transcriptional control and mostly uses post-transcriptional regulation of gene expression, although the molecular mechanisms of the process are still poorly understood. Treatments of leishmaniasis, pathologies associated with Leishma...

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Bibliographic Details
Main Authors: Sneider Alexander Gutierrez Guarnizo, Elena B. Tikhonova, Andrey L. Karamyshev, Carlos E. Muskus, Zemfira N. Karamysheva
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38221-1