Leveraging explainable AI for gut microbiome-based colorectal cancer classification

Abstract Studies have shown a link between colorectal cancer (CRC) and gut microbiome compositions. In these studies, machine learning is used to infer CRC biomarkers using global explanation methods. While these methods allow the identification of bacteria generally correlated with CRC, they fail t...

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Bibliographic Details
Main Authors: Ryza Rynazal, Kota Fujisawa, Hirotsugu Shiroma, Felix Salim, Sayaka Mizutani, Satoshi Shiba, Shinichi Yachida, Takuji Yamada
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-02858-4