HIV-Associated Insults Modulate ADAM10 and Its Regulator Sirtuin1 in an NMDA Receptor-Dependent Manner

HIV-Associated Insults Modulate ADAM10 and Its Regulator Sirtuin1 in an NMDA Receptor-Dependent Manner

Neurologic deficits associated with human immunodeficiency virus (HIV) infection impact about 50% of persons with HIV (PWH). These disorders, termed HIV-associated neurocognitive disorders (HAND), possess neuropathologic similarities to Alzheimer’s disease (AD), including intra- and extracellular am...

Full description

Bibliographic Details
Main Authors: Claudia Lopez Lloreda, Sarah Chowdhury, Shivesh Ghura, Elena Alvarez-Periel, Kelly Jordan-Sciutto
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
HIV
HIV-associated neurocognitive disorders
amyloid precursor protein processing
ADAM10
Sirtuin1
Online Access:https://www.mdpi.com/2073-4409/11/19/2962

Internet

https://www.mdpi.com/2073-4409/11/19/2962

Similar Items