Hepatic protective effect of grape seed proanthocyanidin extract against Gleevec-induced apoptosis, liver Injury and Ki67 alterations in rats

ABSTRACT Gleevec (imatinib) is an antineoplastic chemotherapeutic agent used in the treatment of many types of cancer. The current study was conducted to examine the possible modifying effects of grape seeds proanthocyandins extract (GSPE) against apoptosis, liver injury and Ki67 alterations induced...

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Bibliographic Details
Main Authors: Nawal Mohammed Al-Rasheed, Thanaa Ahmed El-Masry, Ehab Tousson, Hanan Mohammad Hassan, Areej Al-Ghadeer
Format: Article
Language:English
Published: Universidade de São Paulo 2018-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200612&lng=en&tlng=en