Decrease in multiple complement proteins associated with development of islet autoimmunity and type 1 diabetes

Decrease in multiple complement proteins associated with development of islet autoimmunity and type 1 diabetes

Summary: Type 1 diabetes (T1D) is a chronic condition caused by autoimmune destruction of the insulin-producing pancreatic β cells. While it is known that gene-environment interactions play a key role in triggering the autoimmune process leading to T1D, the pathogenic mechanism leading to the appear...

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Bibliographic Details
Main Authors: Bobbie-Jo M. Webb-Robertson, Ernesto S. Nakayasu, Fran Dong, Kathy C. Waugh, Javier E. Flores, Lisa M. Bramer, Athena A. Schepmoes, Yuqian Gao, Thomas L. Fillmore, Suna Onengut-Gumuscu, Ashley Frazer-Abel, Stephen S. Rich, V. Michael Holers, Thomas O. Metz, Marian J. Rewers
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Immunology
Diabetology
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223028468

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223028468

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