Genotoxic and cytotoxic evaluation of venlafaxine in an acute and a subchronic assay in mouse

Abstract The present research was made to determine the micronuclei and cytotoxic capacity of the antidepressant venlafaxine in an in vivo acute and subchronic assays in mouse. In the first study, we administered once 5, 50, and 250 mg/kg of the drug, and included a negative and a daunorubicin treat...

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Main Authors: E. Madrigal-Bujaidar, P. Gómez-González, S. Camacho-Cantera, J. A. Morales-González, E. Madrigal-Santillán, I. Álvarez-González
Format: Article
Language:English
Published: Instituto Internacional de Ecologia 2021-12-01
Series:Brazilian Journal of Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842024000100153&tlng=en