Cellular and molecular effect of MEHP Involving LXRα in human fetal testis and ovary.

Phthalates have been shown to have reprotoxic effects in rodents and human during fetal life. Previous studies indicate that some members of the nuclear receptor (NR) superfamilly potentially mediate phthalate effects. This study aimed to assess if expression of these nuclear receptors are modulated...

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Main Authors: Vincent Muczynski, Charlotte Lecureuil, Sébastien Messiaen, Marie-Justine Guerquin, Thierry N'tumba-Byn, Delphine Moison, Wassim Hodroj, Hinde Benjelloun, Jan Baijer, Gabriel Livera, René Frydman, Alexandra Benachi, René Habert, Virginie Rouiller-Fabre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3484128?pdf=render