Plasma interferon-γ concentration: a potential biomarker of disease activity of systemic chronic active Epstein-Barr virus infection

Plasma interferon-γ concentration: a potential biomarker of disease activity of systemic chronic active Epstein-Barr virus infection

Systemic chronic active Epstein-Barr virus infection (sCAEBV) is an intractable disease that present activated EBV-infected T- or NK-cells and their clonal proliferation. When inflammatory symptoms persist and proceed, a lethal complication of hemophagocytic lymphohistiocytosis (HLH) develops, but i...

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Bibliographic Details
Main Authors: Yu Uemura, Ayaka Ohashi, Mayumi Yoshimori, Miwako Nishio, Tsuneaki Hirakawa, Norio Shimizu, Naomi Wada, Ken-Ichi Imadome, Ayako Arai
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Virology
Subjects:
systemic chronic active Epstein-Barr virus infection (sCAEBV)
Epstein- Barr virus
T cell
NK cell
interferon-γ
hemophagocytic lymphohistiocytosis (HLH)
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.999929/full

Internet

https://www.frontiersin.org/articles/10.3389/fviro.2022.999929/full

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