PAK6: a potential anti-cancer target

p21-activated kinase 6 (PAK6) is a member of the PAK family of serine/threonine kinases that are known effectors of Rho GTPases Cdc42 and Rac. PAKs regulate a large number of complex cellular mechanisms, including cell motility, morphology, and tumor development. PAK6, initially cloned as an interac...

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Bibliographic Details
Main Authors: Chan-Chan Gong, Tong-Tong Li, Dong-Sheng Pei
Format: Article
Language:English
Published: Universidade de São Paulo 2020-03-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100700&tlng=en