Specific CD8<sup>+</sup> TCR Repertoire Recognizing Conserved Antigens of SARS-CoV-2 in Unexposed Population: A Prerequisite for Broad-Spectrum CD8<sup>+</sup> T Cell Immunity

Specific CD8<sup>+</sup> TCR Repertoire Recognizing Conserved Antigens of SARS-CoV-2 in Unexposed Population: A Prerequisite for Broad-Spectrum CD8<sup>+</sup> T Cell Immunity

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed variants escaping neutralization antibody immunity established against the original virus. An understanding of broad-spectrum adaptive immunity, including CD8<sup>+</sup> T cell immunity to wide range...

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Bibliographic Details
Main Authors: Wei Hu, Meifang He, Xiaoning Wang, Qiang Sun, Ming Kuang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
SARS-CoV-2
broad-spectrum adaptive immunity
CD8<sup>+</sup> T cell
TCR repertoire
vaccine
Online Access:https://www.mdpi.com/2076-393X/9/10/1093

Internet

https://www.mdpi.com/2076-393X/9/10/1093

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