Sirtuins promote brain homeostasis, preventing Alzheimer’s disease through targeting neuroinflammation

Both basic pathomechanisms underlying Alzheimer’s disease and some premises for stipulating a possible preventive role of some sirtuins, especially SIRT1 and SIRT3, protective against Alzheimer’s disease-related pathology, are discussed in this article. Sirtuins can inhibit some processes that under...

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Bibliographic Details
Main Authors: Mateusz Watroba, Dariusz Szukiewicz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.962769/full