New Metrics for Evaluating Viral Respiratory Pathogenesis.

Viral pathogenesis studies in mice have relied on markers of severe systemic disease, rather than clinically relevant measures, to evaluate respiratory virus infection; thus confounding connections to human disease. Here, whole-body plethysmography was used to directly measure changes in pulmonary f...

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Bibliographic Details
Main Authors: Vineet D Menachery, Lisa E Gralinski, Ralph S Baric, Martin T Ferris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0131451