PLK1 phosphorylates RhoGDI1 and promotes cancer cell migration and invasion

PLK1 phosphorylates RhoGDI1 and promotes cancer cell migration and invasion

Abstract Background Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays an important role in diverse cellular processes by regulating Rho guanosine triphosphate (GTP)ases activity. RhoGDI1 phosphorylation regulates the spatiotemporal activation of Rho GTPases during cell migration. In th...

Full description

Bibliographic Details
Main Authors: Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho, Hee Gu Lee
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cancer Cell International
Subjects:
PLK1
RhoGDI1
RhoA
Migration
Cancer
Online Access:https://doi.org/10.1186/s12935-024-03254-z

Internet

https://doi.org/10.1186/s12935-024-03254-z

Similar Items