Epigenetic regulation of mesenchymal stem cell aging through histone modifications

Stem cell senescence and exhaustion, a hallmark of aging, lead to declines in tissue repair and regeneration in aged individuals. Emerging evidence has revealed that epigenetic regulation plays critical roles in the self-renew, lineage-commitment, survival, and function of stem cells. Moreover, epig...

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Bibliographic Details
Main Authors: Yanping Sun, Haoyu Zhang, Tao Qiu, Li Liao, Xiaoxia Su
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-11-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222003038