Role of tissue-factor bearing extracellular vesicles released from ovarian cancer cells in platelet aggregation in vitro and venous thrombosis in mice

Role of tissue-factor bearing extracellular vesicles released from ovarian cancer cells in platelet aggregation in vitro and venous thrombosis in mice

Objective: Venous thromboembolism (VTE) contributes to morbidity and mortality in women with ovarian cancer. Underlying mechanisms of venous thrombosis in ovarian cancer are not well-understood. The aim of this study was to identify the potential role of tissue factor (TF)-bearing extracellular vesi...

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Bibliographic Details
Main Authors: Tomoyuki Sasano, Min Soon Cho, Cristian Rodriguez-Aguayo, Emine Bayraktar, Mana Taki, Vahid Afshar-Kharghan, Anil K. Sood
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Thrombosis Update
Subjects:
Extracellular vesicles
Cell-derived microparticles
Tissue factor
Ovarian neoplasms
Thrombosis
Platelet aggregation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666572720300201

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http://www.sciencedirect.com/science/article/pii/S2666572720300201

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