Cysteine Oxidations in Mitochondrial Membrane Proteins: The Case of VDAC Isoforms in Mammals

Cysteine Oxidations in Mitochondrial Membrane Proteins: The Case of VDAC Isoforms in Mammals

Cysteine residues are reactive amino acids that can undergo several modifications driven by redox reagents. Mitochondria are the source of an abundant production of radical species, and it is surprising that such a large availability of highly reactive chemicals is compatible with viable and active...

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Bibliographic Details
Main Authors: Simona Reina, Maria Gaetana Giovanna Pittalà, Francesca Guarino, Angela Messina, Vito De Pinto, Salvatore Foti, Rosaria Saletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cysteine overoxidation
outer mitochondrial membrane
voltage-dependent anion selective channel isoforms
Orbitrap Fusion Tribrid
posttranslational modification
ROS
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00397/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00397/full

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