Recombinant Aflatoxin-Degrading F<sub>420</sub>H<sub>2</sub>-Dependent Reductase from <i>Mycobacterium smegmatis</i> Protects Mammalian Cells from Aflatoxin Toxicity

Recombinant Aflatoxin-Degrading F<sub>420</sub>H<sub>2</sub>-Dependent Reductase from <i>Mycobacterium smegmatis</i> Protects Mammalian Cells from Aflatoxin Toxicity

Aflatoxins are carcinogenic secondary metabolites of fungi that contaminate many staple crops and foods. Aflatoxin contamination is a worldwide problem, especially in developing countries, posing health hazards, e.g., causing aflatoxicosis and hepatocellular carcinoma, and even death. Biological sol...

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Bibliographic Details
Main Authors: Che-Hsing Li, Wei-Yang Li, I-Ning Hsu, Yung-Yu Liao, Chi-Ya Yang, Matthew C. Taylor, Yu-Fan Liu, Wei-Hao Huang, Hsiang-Hua Chang, Ho-Lo Huang, Shao-Chi Lo, Ting-Yu Lin, Wei-Che Sun, Ya-Yi Chuang, Yu-Chieh Yang, Ru-Huei Fu, Rong-Tzong Tsai
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Toxins
Subjects:
aflatoxin B1
F<sub>420</sub>H<sub>2</sub>-dependent reductase
MSMEG_5998
thioredoxin
deazaflavin
Online Access:https://www.mdpi.com/2072-6651/11/5/259

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https://www.mdpi.com/2072-6651/11/5/259

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