Integrated spatial analysis of gene mutation and gene expression for understanding tumor diversity in formalin-fixed paraffin-embedded lung adenocarcinoma
IntroductionA deeper understanding of intratumoral heterogeneity is essential for prognosis prediction or accurate treatment plan decisions in clinical practice. However, due to the cross-links and degradation of biomolecules within formalin-fixed paraffin-embedded (FFPE) specimens, it is challengin...
Main Authors: | Miki Yamazaki, Masahito Hosokawa, Hiroko Matsunaga, Koji Arikawa, Kazuya Takamochi, Kenji Suzuki, Takuo Hayashi, Hideki Kambara, Haruko Takeyama |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Oncology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.936190/full |
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