The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization studyResearch in context

The causal effects of lipid traits on kidney function in Africans: bidirectional and multivariable Mendelian-randomization studyResearch in context

Summary: Background: Observational studies have investigated the effect of serum lipids on kidney function, but these findings are limited by confounding, reverse causation and have reported conflicting results. Mendelian randomization (MR) studies address this confounding problem. However, they ha...

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Bibliographic Details
Main Authors: Christopher Kintu, Opeyemi Soremekun, Abram B. Kamiza, Allan Kalungi, Richard Mayanja, Robert Kalyesubula, Bernard Bagaya S, Daudi Jjingo, June Fabian, Dipender Gill, Moffat Nyirenda, Dorothea Nitsch, Tinashe Chikowore, Segun Fatumo
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:EBioMedicine
Subjects:
Serum lipids
eGFR
Chronic kidney disease
Kidney function
Two-sample Mendelian Randomization
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001020

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http://www.sciencedirect.com/science/article/pii/S2352396423001020

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