Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing

Transcript shortening via alternative polyadenylation promotes gene expression during fracture healing

Abstract Maturation of the 3′ end of almost all eukaryotic messenger RNAs (mRNAs) requires cleavage and polyadenylation. Most mammalian mRNAs are polyadenylated at different sites within the last exon, generating alternative polyadenylation (APA) isoforms that have the same coding region but distinc...

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Bibliographic Details
Main Authors: Deepak Kumar Khajuria, Irena Nowak, Ming Leung, Vengadeshprabhu Karuppagounder, Yuka Imamura, Christopher C. Norbury, Fadia Kamal, Reyad A. Elbarbary
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00236-7

Internet

https://doi.org/10.1038/s41413-022-00236-7

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