Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes

Neurofilament light chain and α-synuclein RT-QuIC as differential diagnostic biomarkers in parkinsonisms and related syndromes

Abstract Neurofilament light chain (NfL) and α-synuclein oligomeric seeds (α-syn-s) are promising biomarkers for patients with parkinsonism. We assessed their performance in discriminating Parkinson disease (PD) from atypical parkinsonisms (APDs) and evaluated the association between NfL levels and...

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Main Authors: Corinne Quadalti, Giovanna Calandra-Buonaura, Simone Baiardi, Andrea Mastrangelo, Marcello Rossi, Corrado Zenesini, Giulia Giannini, Niccolò Candelise, Luisa Sambati, Barbara Polischi, Giuseppe Plazzi, Sabina Capellari, Pietro Cortelli, Piero Parchi
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00232-4

Internet

https://doi.org/10.1038/s41531-021-00232-4

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