Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs

Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs

Mesencephalic astrocyte derived neurotrophic factor (MANF) and cerebral dopamine neurotrophic factor (CDNF) are novel evolutionary conserved trophic factors, which exhibit cytoprotective activity via negative regulation of unfolded protein response (UPR) and inflammation. Despite multiple reports de...

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Bibliographic Details
Main Authors: Julia Konovalova, Dmytro Gerasymchuk, Sergio Navarette Arroyo, Sven Kluske, Francesca Mastroianni, Alba Vargas Pereyra, Andrii Domanskyi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
mesencephalic astrocyte derived neurotrophic factor
MANF
cerebral dopamine neurotrophic factor
CDNF
microRNAs
3′UTR
Online Access:https://www.mdpi.com/1422-0067/22/18/9691

Internet

https://www.mdpi.com/1422-0067/22/18/9691

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