Mitochondrial DNA Variants and Common Diseases: A Mathematical Model for the Diversity of Age-Related mtDNA Mutations

Mitochondrial DNA Variants and Common Diseases: A Mathematical Model for the Diversity of Age-Related mtDNA Mutations

The mitochondrion is the only organelle in the human cell, besides the nucleus, with its own DNA (mtDNA). Since the mitochondrion is critical to the energy metabolism of the eukaryotic cell, it should be unsurprising, then, that a primary driver of cellular aging and related diseases is mtDNA instab...

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Bibliographic Details
Main Authors: Huanzheng Li, Jesse Slone, Lin Fei, Taosheng Huang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
mitochondria
mitochondrial genetics
aging
cancer
diabetes
mutation
Online Access:https://www.mdpi.com/2073-4409/8/6/608

Internet

https://www.mdpi.com/2073-4409/8/6/608

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