DT-13 Inhibits Proliferation and Metastasis of Human Prostate Cancer Cells Through Blocking PI3K/Akt Pathway

DT-13 Inhibits Proliferation and Metastasis of Human Prostate Cancer Cells Through Blocking PI3K/Akt Pathway

DT-13, a saponin monomer 13 from the dwarf lilyturf tuber, was reported to exhibit anti-inflammatory, hepatoprotective, cardioprotective as well as antitumor activities in a number of tumor cells. Prostate cancer is the second leading cause of cancer death in males, discovery of novel antitumor drug...

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Bibliographic Details
Main Authors: Zhengming Wang, Yingying Wang, Shan Zhu, Yao Liu, Xin Peng, Shaolu Zhang, Zhe Zhang, Yuling Qiu, Meihua Jin, Ran Wang, Yuxu Zhong, Dexin Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
DT-13
prostate cancer
anti-proliferation
anti-metastasis
apoptosis
PI3K/Akt pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01450/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01450/full

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