Coupling Between Protein Level Selection and Codon Usage Optimization in the Evolution of Bacteria and Archaea

ABSTRACT The relationship between the selection affecting codon usage and selection on protein sequences of orthologous genes in diverse groups of bacteria and archaea was examined by using the Alignable Tight Genome Clusters database of prokaryote genomes. The codon usage bias is generally low, wit...

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Bibliographic Details
Main Authors: Wenqi Ran, David M. Kristensen, Eugene V. Koonin
Format: Article
Language:English
Published: American Society for Microbiology 2014-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00956-14