Retention and Fouling during Nanoparticle Filtration: Implications for Membrane Purification of Biotherapeutics

One major challenge in the development of nanoparticle-based therapeutics, including viral vectors for the delivery of gene therapies, is the development of cost-effective purification technologies. The objective of this study was to examine fouling and retention behaviors during the filtration of m...

Full description

Bibliographic Details
Main Authors: Liang-Kai Chu, S. Ranil Wickramasinghe, Xianghong Qian, Andrew L. Zydney
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/12/3/299