Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of Schistosoma mansoni Infection in a Low Endemic Area in Brazil

Performance of an Ultra-Sensitive Assay Targeting the Circulating Anodic Antigen (CAA) for Detection of Schistosoma mansoni Infection in a Low Endemic Area in Brazil

Techniques with high sensitivity and specificity are required for an accurate diagnosis in low-transmission settings, where the conventional parasitological methods are insensitive. We determined the accuracy of an up-converting phosphor-lateral flow circulating anodic antigen (UCP-LF CAA) assay in...

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Bibliographic Details
Main Authors: Mariana Silva Sousa, Govert J. van Dam, Marta Cristhiany Cunha Pinheiro, Claudia J. de Dood, Jose Mauro Peralta, Regina Helena Saramago Peralta, Elizabeth de Francesco Daher, Paul L. A. M. Corstjens, Fernando Schemelzer Moraes Bezerra
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
circulating anodic antigen (CAA)
diagnosis
up-converting phosphor lateral-flow assay
POC-CCA test
polymerase chain reaction (PCR)
Schistosoma mansoni
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00682/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00682/full

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