Caloric restriction improves glycaemic control without reducing plasma branched-chain amino acids or keto-acids in obese men

Abstract Higher plasma leucine, isoleucine and valine (BCAA) concentrations are associated with diabetes, obesity and insulin resistance (IR). Here, we evaluated the effects of 6-weeks very-low calorie diet (VLCD) upon fasting BCAA in overweight (OW) non-diabetic men, to explore associations between...

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Bibliographic Details
Main Authors: M. H. Sayda, M. H. Abdul Aziz, N. Gharahdaghi, D. J. Wilkinson, P. L. Greenhaff, B. E. Phillips, K. Smith, I. Idris, P. J. Atherton
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21814-z