Basket to Purkinje Cell Inhibitory Ephaptic Coupling Is Abolished in Episodic Ataxia Type 1
Dominantly inherited missense mutations of the <i>KCNA1</i> gene, which encodes the K<sub>V</sub>1.1 potassium channel subunit, cause Episodic Ataxia type 1 (EA1). Although the cerebellar incoordination is thought to arise from abnormal Purkinje cell output, the underlying fu...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-05-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/12/10/1382 |