Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women

Polygenic Models Partially Predict Muscle Size and Strength but Not Low Muscle Mass in Older Women

Background: Heritability explains 45-82% of muscle mass and strength variation, yet polygenic models for muscle phenotypes in older women are scarce. Therefore, the objective of the present study was to (1) assess if total genotype predisposition score (GPS<sub>TOTAL</sub>) for a set of...

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Bibliographic Details
Main Authors: Praval Khanal, Christopher I. Morse, Lingxiao He, Adam J. Herbert, Gladys L. Onambélé-Pearson, Hans Degens, Martine Thomis, Alun G. Williams, Georgina K. Stebbings
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Genes
Subjects:
polygenic model
predisposing allele
skeletal muscle phenotypes
low and high muscle mass
Online Access:https://www.mdpi.com/2073-4425/13/6/982

Internet

https://www.mdpi.com/2073-4425/13/6/982

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