Chronological Age Prediction: Developmental Evaluation of DNA Methylation-Based Machine Learning Models

Chronological Age Prediction: Developmental Evaluation of DNA Methylation-Based Machine Learning Models

Epigenetic clock, a highly accurate age estimator based on DNA methylation (DNAm) level, is the basis for predicting mortality/morbidity and elucidating the molecular mechanism of aging, which is of great significance in forensics, justice, and social life. Herein, we integrated machine learning (ML...

Full description

Bibliographic Details
Main Authors: Haoliang Fan, Qiqian Xie, Zheng Zhang, Junhao Wang, Xuncai Chen, Pingming Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
DNA methylation
CpG
chronological age prediction
machine learning
stepwise regression
support vector regression
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.819991/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.819991/full

Similar Items