Shall I trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection

Shall I trust the report? Variable performance of Sanger sequencing revealed by deep sequencing on HIV drug resistance mutation detection

Background: The clinical utilisation of deep sequencing in HIV treatment has been hindered due to its unknown correlation with standard Sanger genotyping and the undetermined value of minority drug resistance mutation (DRM) detection. Objectives: To compare deep sequencing performance to standard Sa...

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Bibliographic Details
Main Authors: Nan-Yu Chen, Shu-Wei Kao, Zhuo-Hao Liu, Ting-Shu Wu, Chia-Lung Tsai, Hsi-Hsun Lin, Wing-Wai Wong, Yea-Yuan Chang, Shu-Sheng Chen, Stephane Wen-Wei Ku
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:International Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S120197122030062X

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http://www.sciencedirect.com/science/article/pii/S120197122030062X

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