Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

Trained immunity is regulated by T cell-induced CD40-TRAF6 signaling

Summary: Trained immunity is characterized by histone modifications and metabolic changes in innate immune cells following exposure to inflammatory signals, leading to heightened responsiveness to secondary stimuli. Although our understanding of the molecular regulation of trained immunity has incre...

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Bibliographic Details
Main Authors: Maaike M.E. Jacobs, Rianne J.F. Maas, Inge Jonkman, Yutaka Negishi, Willem Tielemans Zamora, Cansu Yanginlar, Julia van Heck, Vasiliki Matzaraki, Joost H.A. Martens, Marijke Baltissen, Michiel Vermeulen, Judit Morla-Folch, Anna Ranzenigo, William Wang, Martin Umali, Jordi Ochando, Johan van der Vlag, Luuk B. Hilbrands, Leo A.B. Joosten, Mihai G. Netea, Willem J.M. Mulder, Mandy M.T. van Leent, Musa M. Mhlanga, Abraham J.P. Teunissen, Nils Rother, Raphaël Duivenvoorden
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724010155

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http://www.sciencedirect.com/science/article/pii/S2211124724010155

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