A Circ-0007022/miR-338-3p/Neuropilin-1 Axis Reduces the Radiosensitivity of Esophageal Squamous Cell Carcinoma by Activating Epithelial-To-Mesenchymal Transition and PI3K/AKT Pathway

A Circ-0007022/miR-338-3p/Neuropilin-1 Axis Reduces the Radiosensitivity of Esophageal Squamous Cell Carcinoma by Activating Epithelial-To-Mesenchymal Transition and PI3K/AKT Pathway

Radiotherapy resistance is an important cause of treatment failure in esophageal squamous cell carcinoma (ESCC). Circular RNAs have attracted a lot of attention in cancer research, but their role in ESCC radiosensitivity has not been elucidated yet. Here, we aimed to evaluated the functional impacts...

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Bibliographic Details
Main Authors: Junpeng Zhang, Yanyan Yu, Xiaoyang Yin, Lei Feng, Zhe Li, Xiaomeng Liu, Xinshuang Yu, Baosheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
circ-0007022
miR-338-3p
neuropilin-1
radiosensitivity
ESCC
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.854097/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.854097/full

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