Effects of asparaginases and L-carnitine on Western-diet-induced hepatosteatosis in mice [version 1; peer review: 1 approved, 2 approved with reservations]

Abstract Background: Asparaginases are common chemotherapeutic agents used for the treatment of acute lymphoblastic leukemia as a single or combinational therapy. Accompanying hepatotoxicity makes its use in elderly patients with pre-conditions, as obesity or other hepatopathies, difficult. Various...

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Bibliographic Details
Main Authors: Julia Steitz, Mamdouh Afify, Rene Tolba, Albrecht Eisert, Martina Hüffel, Mona Ali Mahmoud Assar, Ralf Weiskirchen
Format: Article
Language:English
Published: F1000 Research Ltd 2022-02-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/11-128/v1