The Potential of Nrf2 Activation as a Therapeutic Target in Systemic Lupus Erythematosus

Inflammation and oxidative stress are well established in systemic lupus erythematosus (SLE) and are critical to the pathogenesis of autoimmune diseases. The transcription factor NF-E2 related factor 2 (Nrf2) is a central regulator of cellular anti-oxidative responses, inflammation, and restoration...

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Bibliographic Details
Main Authors: Michelle T. Barati, Dawn J. Caster
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/2/151